The function of SLC25A16 (solute carrier family 25 member 16, Ensembl gene identifier ENSG00000122912) is as follows. Mitochondrial inner membrane transporter that regulates coenzyme A homeostasis between cytosol and mitochondria (PubMed:11158296, PubMed:36316571, PubMed:40925986). Could mediate the import of coenzyme A from the cytosol into the mitochondrial matrix (PubMed:11158296, PubMed:40925986). Alternatively, it could function in the export of 3'-dephospho-CoA from the mitochondrial matrix to the cytosol (PubMed:36316571). {ECO:0000269|PubMed:11158296, ECO:0000269|PubMed:36316571, ECO:0000269|PubMed:40925986}.