The function of ENSG00000125458 (NT5C, 5', 3'-nucleotidase, cytosolic) is as follows. Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP (Ref.12). Also dephosphsphorylates dTMP, exhibits intermediate activity towards dGMP, and low activity towards dCMP and dAMP (By similarity). .