Shows strong preference for glycerophosphocholine. Displays weak activity toward glycerophosphoethanolamine and no detectable activity toward glycerophosphoglycerol, glycerophosphoserine, or glycerophosphoinosito. May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity. . This is the function of Ensembl gene identifier ENSG00000125772 (GPCPD1, glycerophosphocholine phosphodiesterase 1).