The function of MTSS2 (MTSS I-BAR domain containing 2, ENSG00000132613) is as follows. Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation (PubMed:14752106). May function in actin bundling (PubMed:14752106). .