The function of KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2, ENSG00000136240) is as follows. Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi (PubMed:1325562, PubMed:18086916, PubMed:33053334). Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity). {ECO:0000250|UniProtKB:Q5ZKX9, ECO:0000269|PubMed:1325562, ECO:0000269|PubMed:18086916, ECO:0000269|PubMed:33053334}.