The function of NTRK3 (neurotrophic receptor tyrosine kinase 3, Ensembl gene identifier ENSG00000140538) is as follows. Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. .