The function of Ensembl gene identifier ENSG00000140612 (SEC11A, SEC11 homolog A, signal peptidase complex subunit) is as follows. Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:34388369). Specifically cleaves N- terminal signal peptides that contain a hydrophobic alpha-helix (h- region) shorter than 18-20 amino acids (PubMed:34388369). .