The function of SAT2 (spermidine/spermine N1-acetyltransferase family member 2, Ensembl gene identifier ENSG00000141504) is as follows. Catalyzes the N-acetylation of the amino acid thialysine (S- (2-aminoethyl)-L-cysteine), a L-lysine analog with the 4-methylene group substituted with a sulfur (PubMed:15283699). May also catalyze acetylation of polyamines, such as norspermidine, spermidine or spermine (PubMed:12803540). However, ability to acetylate polyamines is weak, suggesting that it does not act as a diamine acetyltransferase in vivo (PubMed:15283699). {ECO:0000269|PubMed:12803540, ECO:0000269|PubMed:15283699}.