The function of ENSG00000146221 (DRC5, dynein regulatory complex subunit 5) is as follows. Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC. May be required for sperm motility. {ECO:0000250|UniProtKB:A6H639, ECO:0000250|UniProtKB:A8HMZ4}.