Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the regulation of cell proliferation and autophagy by promoting the ubiquitination and degradation of SQSTM1 (PubMed:34164402). {ECO:0000269|PubMed:16325183, ECO:0000269|PubMed:34164402}. This is the function of ASB6 (ankyrin repeat and SOCS box containing 6, ENSG00000148331).