The function of ENSG00000148429 (USP6NL, USP6 N-terminal like) is as follows. Acts as a GTPase-activating protein for RAB43, RAB5A and RAB30 (PubMed:11099046, PubMed:16086013, PubMed:17562788, PubMed:17684057). Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. {ECO:0000269|PubMed:11099046, ECO:0000269|PubMed:16086013, ECO:0000269|PubMed:17562788, ECO:0000269|PubMed:17684057}.