The function of PIGF (phosphatidylinositol glycan anchor biosynthesis class F, ENSG00000151665) is as follows. Stabilizing subunit of the ethanolamine phosphate transferase 3 and ethanolamine phosphate transferase 2 complexes that sequentially transfer an ethanolamine phosphate (EtNP) from a phosphatidylethanolamine (PE) to the 6-OH position of the third alpha- 1,2-linked mannose and the second alpha-1,6-linked mannose of a 2-acyl- 6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2- phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1- radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol (also termed H6) intermediate to generate a 2-acyl-6-[6-phosphoethanolamine-alpha-D- mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2- phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1- radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol (also termed H8) (PubMed:15632136). Participates in the tenth and eleventh steps of the glycosylphosphatidylinositol-anchor biosynthesis, in association with PIGO and PIGG, respectively (PubMed:15632136, PubMed:33386993). .