(Microbial infection) Acts as a receptor for respiratory enterovirus D68 (PubMed:39798568, PubMed:40132641). Mechanistically, binds to viral particles and is required for viral cell entry while initial attachment to cells is mainly mediated by interactions with sialic acid (PubMed:40132641). {ECO:0000269|PubMed:39798568, ECO:0000269|PubMed:40132641}. This is the function of MFSD6 (major facilitator superfamily domain containing 6, ENSG00000151690).