AMPK substrate important for exercise capacity and skeletal muscle function. Required for normal contraction-induced signaling. . (Microbial infection) Upon Epstein-Barr virus (EBV) infection, suppresses viral BZLF1 expression and subsequent EBV reactivation by interacting with JUN and inhibiting its transcriptional activator activity on BZLF1 Z promoter. . This is the function of ARK2N (arkadia (RNF111) N-terminal like PKA signaling regulator 2N, Ensembl gene identifier ENSG00000152242).