The function of Ensembl gene identifier ENSG00000153721 (CNKSR3, CNKSR family member 3) is as follows. Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC- regulatory complex (ERC). .