Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1 (PubMed:10438935, PubMed:8777714, PubMed:9841932). May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood (Probable). {ECO:0000269|PubMed:10438935, ECO:0000269|PubMed:8777714, ECO:0000269|PubMed:9841932, ECO:0000305|PubMed:8777714}. This is the function of ENSG00000156886 (ITGAD, integrin subunit alpha D).