The function of Ensembl gene identifier ENSG00000156920 (ADGRG4, adhesion G protein-coupled receptor G4) is as follows. Orphan adhesion G protein-coupled receptor (aGPCR) (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (By similarity). ADGRG4 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity (PubMed:35418677). May be act as sensor of mechanical forces (PubMed:37863265). {ECO:0000250|UniProtKB:Q8CJ12, ECO:0000269|PubMed:35418677, ECO:0000269|PubMed:37863265}.