The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:8647132). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:8647132). RAB28 is required for shedding and phagocytosis of cone cell outer segments (OS) discs in the retina (By similarity). Also participates in nuclear factor kappa-B p65/RELA nuclear transport in endothelial cells (By similarity). {ECO:0000250|UniProtKB:P51158, ECO:0000250|UniProtKB:Q99KL7, ECO:0000269|PubMed:8647132}. This is the function of Ensembl gene identifier ENSG00000157869 (RAB28, RAB28, member RAS oncogene family).