The function of ENSG00000157985 (AGAP1, ArfGAP with GTPase domain, ankyrin repeat and PH domain 1) is as follows. GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)- dependent trafficking of proteins in the endosomal-lysosomal system. .