The function of ENSG00000159314 (ARHGAP27, Rho GTPase activating protein 27) is as follows. Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). .