The function of Ensembl gene identifier ENSG00000160570 (DEDD2, death effector domain containing 2) is as follows. May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.