The function of FBXL13 (F-box and leucine rich repeat protein 13, ENSG00000161040) is as follows. Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Component of the nexin- dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Specifically targets CEP192 isoform 3 for ubiquitin-mediated proteolysis and thereby acts as a regulator of microtubule nucleation activity (PubMed:29348145). {ECO:0000250|UniProtKB:A8JHD7, ECO:0000269|PubMed:29348145}.