[DCD-1]: Found in sweat, has an antimicrobial activity during early bacterial colonization (PubMed:11694882, PubMed:23426625). The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes (PubMed:23426625). Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival (PubMed:23426625). Highly effective against E.coli, E.faecalis, S.aureus and C.albicans (PubMed:11694882). Optimal pH and salt concentration resemble the conditions in sweat (PubMed:11694882). Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues (PubMed:17448443). {ECO:0000269|PubMed:11694882, ECO:0000269|PubMed:17448443, ECO:0000269|PubMed:23426625}. [Survival-promoting peptide]: Promotes survival of neurons and displays phosphatase activity (PubMed:9736629). It may bind IgG (PubMed:9736629). . This is the function of Ensembl gene identifier ENSG00000161634 (DCD, dermcidin).