The function of ASB16 (ankyrin repeat and SOCS box containing 16, Ensembl gene identifier ENSG00000161664) is as follows. May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. .