Acts as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization (PubMed:32128961). Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (By similarity). May play a role in osteogenesis of dental tissue-derived mesenchymal stem cells (By similarity). {ECO:0000250|UniProtKB:B2RY71, ECO:0000269|PubMed:32128961}. This is the function of DNAI3 (dynein axonemal intermediate chain 3, Ensembl gene identifier ENSG00000162643).