Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens (By similarity). Negatively regulates the antiviral response by inhibiting activation of IRF7 transcription factor (By similarity). . This is the function of Ensembl gene identifier ENSG00000162654 (GBP4, guanylate binding protein 4).