The function of LMX1A (LIM homeobox transcription factor 1 alpha, Ensembl gene identifier ENSG00000162761) is as follows. Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity). .