The function of Ensembl gene identifier ENSG00000162819 (BROX, BRO1 domain and CAAX motif containing) is as follows. Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane. .