The function of Ensembl gene identifier ENSG00000162944 (RFTN2, raftlin family member 2) is as follows. Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling. .