[CNP-22]: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation (By similarity). May also be vasoactive and natriuretic (PubMed:1672777). Acts by specifically binding and stimulating NPR2 to produce cGMP (PubMed:1672777, PubMed:21098034). Binds the clearance receptor NPR3 (PubMed:11533490). {ECO:0000250|UniProtKB:Q61839, ECO:0000269|PubMed:11533490, ECO:0000269|PubMed:1672777, ECO:0000269|PubMed:21098034}. This is the function of Ensembl gene identifier ENSG00000163273 (NPPC, natriuretic peptide C).