The function of MTHFD2L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like, ENSG00000163738) is as follows. Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. .