May play a role in myoblast differentiation. When unphosphorylated, associates with an ELAVL1-containing complex, which stabilizes cyclin mRNA and ensuring cell proliferation. Phosphorylation by AKT2 impairs this association, leading to CCND1 mRNA destabilization and progression towards differentiation. . [Isoform PTX2C]: Involved in the establishment of left-right asymmetry in the developing embryo. . This is the function of PITX2 (paired like homeodomain 2, ENSG00000164093).