Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway (PubMed:28388415). May also regulate other G protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable). . This is the function of LMBRD2 (LMBR1 domain containing 2, Ensembl gene identifier ENSG00000164187).