The function of Ensembl gene identifier ENSG00000164675 (IQUB, IQ motif and ubiquitin domain containing) is as follows. Adapter protein that anchors the radial spoke 1 (RS1) complex to the A microtubule of outer doublet microtubules in axonemes (PubMed:36355624). The triple radial spokes (RS1, RS2 and RS3) are required to modulate beating of the sperm flagellum (PubMed:36355624). May play a role in inhibiting signaling via MAPK1/ERK2 and MAPK3/ERK1 (PubMed:36355624). Additionally, may play a role in the functioning of cilia (By similarity). Not required for the functioning of tracheal or ependymal cilia (By similarity). {ECO:0000250|UniProtKB:Q8CDK3, ECO:0000269|PubMed:36355624}.