Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as BIK, DIRAS2 and RPN1 (PubMed:24337577, PubMed:31387940, PubMed:38574733). The ECS(ASB11) complex acts as a regulator of the endoplasmic reticulum unfolded protein response by mediating ubiquitination and degradation of BIK (PubMed:31387940). {ECO:0000269|PubMed:24337577, ECO:0000269|PubMed:31387940, ECO:0000269|PubMed:38574733}. This is the function of ENSG00000165192 (ASB11, ankyrin repeat and SOCS box containing 11).