Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation (PubMed:15885354, PubMed:15917256). In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability (PubMed:22405205). {ECO:0000269|PubMed:15885354, ECO:0000269|PubMed:15917256, ECO:0000269|PubMed:22405205}. This is the function of HEPACAM (hepatic and glial cell adhesion molecule, ENSG00000165478).