The function of ENSG00000165861 (ZFYVE1, zinc finger FYVE-type containing 1) is as follows. Plays a role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:30970241). Regulates the morphology, size and distribution of LDs (PubMed:30970241, PubMed:31293035). Mediates the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts by forming a complex with RAB18 and ZW10 (PubMed:30970241). Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through FYVE-type zinc finger (PubMed:11256955, PubMed:11739631). {ECO:0000269|PubMed:11256955, ECO:0000269|PubMed:11739631, ECO:0000269|PubMed:30970241, ECO:0000269|PubMed:31293035}. (Microbial infection) Upon SARS coronavirus-2/SARS-CoV-2 infection, mediates through binding with non-structural protein 6 (nsp6) the replication organelle-lipid droplet association required to sustain viral replication. .