The function of ENSG00000167680 (SEMA6B, semaphorin 6B) is as follows. Functions as a cell surface repellent for mossy fibers of developing neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons. . (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium. .