IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration (PubMed:24003225). . This is the function of Ensembl gene identifier ENSG00000167779 (IGFBP6, insulin like growth factor binding protein 6).