The function of ULK4 (unc-51 like kinase 4, ENSG00000168038) is as follows. Pseudokinase that acts as a molecular adapter in the smoothened signaling pathway (PubMed:38096226). Required to relieve inhibition of the GLI2 transcription factor in the presence of hedgehog (DHH, IHH or SHH) ligand: acts by mediating the association between STK36 and its ligand GLI2 in ciliary tip, promoting GLI2 phosphorylation and dissociation from SUFU inhibitor, followed by GLI2 translocation to the nucleus (PubMed:38096226). .