The function of GNG4 (G protein subunit gamma 4, Ensembl gene identifier ENSG00000168243) is as follows. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. .