The function of Ensembl gene identifier ENSG00000169777 (TAS2R1, taste 2 receptor member 1) is as follows. Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.