The function of NAT1 (N-acetyltransferase 1, Ensembl gene identifier ENSG00000171428) is as follows. Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.