The function of Ensembl gene identifier ENSG00000172061 (LRRC15, leucine rich repeat containing 15) is as follows. (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein (PubMed:36228039, PubMed:36735681, PubMed:36757924). Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells (PubMed:36228039, PubMed:36757924). {ECO:0000269|PubMed:36228039, ECO:0000269|PubMed:36735681, ECO:0000269|PubMed:36757924}.