The function of Ensembl gene identifier ENSG00000172137 (CALB2, calbindin 2) is as follows. Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways (PubMed:2001709). Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory (By similarity). During embryonic development, it facilitates neuronal differentiation and maturation (By similarity). {ECO:0000250|UniProtKB:P47728, ECO:0000250|UniProtKB:Q08331, ECO:0000269|PubMed:2001709}.