Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling. {ECO:0000250, ECO:0000269|PubMed:18847501, ECO:0000269|PubMed:22467880}. This is the function of ZBTB35 (zinc finger and BTB domain containing 35, Ensembl gene identifier ENSG00000172262).