RSPH9
radial spoke head component 9
Ensembl: ENSG00000172426UniProt: Q9H1X1GeneCards: RSPH9HGNC: RSPH9Project Score: SIDG33463
Description
Clinical precedence for drugs with investigational or approved indications targeting according to their curated mechanism of action. Source: ChEMBL.
Drug information | Disease information | Clinical trials information | |||||
|---|---|---|---|---|---|---|---|
Drug | Type | Mechanism Of Action | Action Type | Disease | Phase | Status | Source |
Reported safety effects and risk information for RSPH9. Source: Open Targets.
Safety event | Biosystems | Dosing effects | Experimental studies | Source |
|---|---|---|---|---|
Potent, selective and cell-permeable chemical modulators for RSPH9. Source: Probes & Drugs
Gene Essentiality assessment for RSPH9 obtained through CRISPR loss-of-function screens in a wide range of cancer cell lines. Source: DepMap Portal.
Annotations for RSPH9. Source: UniProt.
Category | GO term | Gene product | Evidence code | Source |
|---|---|---|---|---|
Mutational constraint observed in RSPH9 canonical transcript in natural populations. Source: gnomAD.
Category | Expected SNVs | Observed SNVs | Constraint metrics |
|---|---|---|---|
Structural protein information for RSPH9. Source: UniProt.
Physical and functional molecular interactions with RSPH9. Source: Open Targets, IntAct, Signor, Reactome, String
