The function of ENSG00000172867 (KRT2, keratin 2) is as follows. Structural component of intermediate filaments in suprabasal keratinocytes of stratified epidermis. Forms heteropolymers with type I keratins (e.g., KRT10), assembling into keratin intermediate filament networks that support mechanical integrity and resilience of the differentiating epidermis (PubMed:12598329, PubMed:1380918). Contributes to terminal differentiation and cornification of keratinocytes and plays a role in establishing the epidermal barrier (PubMed:9804344). {ECO:0000269|PubMed:12598329, ECO:0000269|PubMed:1380918, ECO:0000269|PubMed:9804344}.