May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease- independent function in the transport from the endoplasmic reticulum to the Golgi apparatus of secretory cargos, mediated by the GON domain. This is the function of Ensembl gene identifier ENSG00000173157 (ADAMTS20, ADAM metallopeptidase with thrombospondin type 1 motif 20).