The function of CNIH2 (cornichon family AMPA receptor auxiliary protein 2, Ensembl gene identifier ENSG00000174871) is as follows. Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. .